Advance Market Commitments

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In 2005, a CGD Working Group produced an economic and legal framework for funds to incentivize vaccine development. The G-7 Finance Ministers endorsed the approach and five donors (Canada, Italy, Norway, UK and Russia, and the Gates Foundation) committed $1.5 billion to create an incentive for a vaccine against the strains of pneumococcus disease prevalent in low-income countries. For updates, see Advance Market Commitments for Vaccines (, a joint effort of the GAVI Alliance and the World Bank.

Making Markets for Vaccines with an Advance Market Commitment Book CoverMaking a commitment in advance to buy vaccines if and when they are developed would create incentives for industry to increase investment in research and development. New commercial investment would complement funding of research and development (R&D) by public and charitable bodies, accelerating the development of vital new vaccines for the developing world.

This report presents the proposal from theory to practice, by showing how a commitment can be consistent with ordinary legal and budgetary principles. A draft contract term sheet is included, highlighting the key elements of a credible guarantee.

This generation can leave an historic legacy. By creating arrangements that devote the same scientific effort to diseases of the poor as we put into diseases of the rich, we can make a lasting contribution to the defeat of poverty.