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The submission calls upon political leaders to improve the R&D environment for neglected diseases.
As a crucial first step, political leaders must set a public health agenda to establish targeted policies. With these in place, biomedical companies R&D can help address the need for improved therapies through a series of initiatives:
* Product Development Public Private Partnerships (PPPs): These independent organizations can attract public and private funding to finance applied research and development for neglected diseases.
* Advanced Purchasing Commitments (APC): APCs compensate for inadequate market size by specifying price and volume requirements for the development of a certain drug.
* Global Fund for Tropical Diseases: Such a fund makes necessary finances available to countries and communities, so they can purchase new and existing drugs for neglected diseases.
* Tropical Diseases Drug Act: Similar to the Orphan Drug Act, this legislative package would provide incentives to increase R&D for neglected diseases. Key features would include a combination of â€œpush/pullâ€ mechanisms, such as R&D tax credits, grants, reduced regulatory fees, and fast track regulatory approval.
CGD blog posts reflect the views of the authors, drawing on prior research and experience in their areas of expertise. CGD is a nonpartisan, independent organization and does not take institutional positions.